| Date | Location | Result | |
| 03/24/21 | Evansville, IN | NW Missouri State 98, West Liberty 77 | Box score |
| 03/16/21 | West Liberty, W.Va. | West Liberty 78, Hillsdale 61 | Box score |
| 03/14/21 | West Liberty, W.Va. | West Liberty 82, Charleston 63 | Box score |
| 03/13/21 | West Liberty, W.Va. | West Liberty 94, Malone 89 | Box score |
| 03/13/21 | West Liberty, W.Va. | Mercyhurst 62, Fairmont State 58 | Box score |
| 03/07/21 | Wheeling, WV | Fairmont State 102, West Liberty 99 | Box score |
| 03/06/21 | Wheeling, WV | West Liberty 95, Glenville State 92 | Box score |
| 03/06/21 | Wheeling, WV | Fairmont State 84, Charleston 69 | Box score |
| 03/05/21 | Wheeling, WV | West Liberty 102, Concord 68 | Box score |
| 03/05/21 | Wheeling, WV | Glenville State 83, Notre Dame 68 | Box score |
| 03/05/21 | Wheeling, WV | Charleston 86, Wheeling 49 | Box score |
| 03/05/21 | Wheeling, WV | Fairmont State 95, W.Va. State 87 | Box score |
| 03/01/21 | Athens, WV | Concord 107, Davis & Elkins 100 | Box score |
| 3/1/21 | Rex Pyles Arena | Wheeling 97, Alderson Broaddus 91 | Box score |
| 02/20/21 | Athens, WV | Charleston 86, Concord 65 | Box score |
| 2/26/21 | Waco Center - | Fairmont State 100, Glenville State 89 | Box score |
| 02/27/21 | South Euclid, OH | Notre Dame 95, Alderson Broaddus 85 | Box score |
| 02/27/21 | Wheeling, WV | West Liberty 107, Wheeling 88 | Box score |
| 2/27/21 | Institute, WV | Charleston 96, W.Va. State 83 | Box score |
| 02/27/21 | Fairmont, WV | Fairmont State 109, Frostburg State 85 | Box score |
| 02/27/21 | Glenville, WV | Glenville State 100, Concord 81 | Box score |
| 02/25/21 | Frostburg, MD | Wheeling 90, Frostburg State 75 | Box score |
| 2/25/21 | Rex Pyles Arena | Davis & Elkins 80, Alderson Broaddus 79 | Box score |
| 02/24/21 | Elkins, WV | W.Va. State 88, Davis & Elkins 80 | Box score |
| 02/24/21 | Buckhannon, WV | Concord 77, W.Va. Wesleyan 66 | Box score |
| 02/24/21 | West Liberty, W.Va. | West Liberty 126, Fairmont State 96 | Box score |
| 02/24/21 | South Euclid, OH | Notre Dame 84, Frostburg State 76 | Box score |
| 2/24/21 | Rex Pyles Arena | Wheeling 99, Alderson Broaddus 98 | Box score |
| 02/22/21 | Elkins, WV | West Liberty 77, Davis & Elkins 59 | Box score |
| 2/22/21 | Institute, WV | W.Va. State 86, Wheeling 68 | Box score |
| 02/22/21 | South Euclid, OH | Notre Dame 96, Fairmont State 85 | Box score |
| 02/22/21 | Charlotte, NC | Frostburg State 87, Alderson Broaddus 86 | Box score |
| 02/15/21 | Wheeling, WV | Concord 74, Wheeling 73 | Box score |
| 2/20/21 | Institute, WV | W.Va. State 104, W.Va. Wesleyan 92 | Box score |
| 02/20/21 | Wheeling, WV | Notre Dame 76, Wheeling 75 | Box score |
| 02/20/21 | Charlotte, NC | West Liberty 128, Frostburg State 75 | Box score |
| 2/20/21 | Rex Pyles Arena | Fairmont State 79, Alderson Broaddus 78 | Box score |
| 02/17/21 | Wheeling, WV | Wheeling 89, Frostburg State 85 | Box score |
| 02/17/21 | Institute, WV | Concord 96, W.Va. State 81 | Box score |
| 02/17/21 | Charleston, WV | Charleston 109, Davis & Elkins 74 | Box score |
| 02/17/21 | Fairmont, WV | Fairmont State 94, Notre Dame 84 | Box score |
| 02/13/21 | Buckhannon, WV | Charleston 101, W.Va. Wesleyan 85 | Box score |
| 02/13/21 | South Euclid, OH | West Liberty 89, Notre Dame 84 | Box score |
| 02/13/21 | Fairmont, WV | Fairmont State 87, Wheeling 73 | Box score |
| 02/13/21 | Athens, WV | Concord 87, Davis & Elkins 82 | Box score |
| 02/10/21 | Elkins, WV | Davis & Elkins 83, W.Va. Wesleyan 80 | Box score |
| 02/10/21 | West Liberty, W.Va. | West Liberty 119, Wheeling 76 | Box score |
| 02/10/21 | Charleston, WV | Charleston 93, W.Va. State 87 | Box score |
| 02/10/21 | Charlotte, NC | Fairmont State 99, Frostburg State 75 | Box score |
| 2/10/21 | Rex Pyles Arena | Alderson Broaddus 77, Notre Dame 65 | Box score |
| 02/08/21 | Elkins, WV | Notre Dame 98, Davis & Elkins 91 | Box score |
| 02/08/21 | Wheeling, WV | Charleston 73, Wheeling 69 | Box score |
| 02/08/21 | Fairmont, WV | Fairmont State 90, Concord 68 | Box score |
| 02/08/21 | Charlotte, NC | Glenville State 131, Frostburg State 104 | Box score |
| 02/07/21 | West Liberty, W.Va. | West Liberty 111, W.Va. Wesleyan 64 | Box score |
| 2/6/21 | Institute, WV | Fairmont State 82, W.Va. State 76 | Box score |
| 02/06/21 | South Euclid, OH | Notre Dame 71, Concord 56 | Box score |
| 02/06/21 | Wheeling, WV | Wheeling 84, Davis & Elkins 71 | Box score |
| 2/6/21 | Rex Pyles Arena | Alderson Broaddus 102, Glenville State 94 | Box score |
| 02/03/21 | Buckhannon, WV | Wheeling 85, W.Va. Wesleyan 77 | Box score |
| 02/03/21 | West Liberty, W.Va. | West Liberty 117, Alderson Broaddus 78 | Box score |
| 2/3/21 | Waco Center - | Glenville State 91, Notre Dame 80 | Box score |
| 02/03/21 | Fairmont, WV | Charleston 85, Fairmont State 70 | Box score |
| 02/03/21 | Charlotte, NC | Frostburg State 77, W.Va. State 71 | Box score |
| 02/01/21 | West Liberty, W.Va. | West Liberty 117, Glenville State 85 | Box score |
| 02/01/21 | South Euclid, OH | Notre Dame 88, W.Va. Wesleyan 70 | Box score |
| 02/01/21 | Fairmont, WV | Fairmont State 101, Alderson Broaddus 67 | Box score |
| 01/30/21 | Athens, WV | Concord 69, Frostburg State 60 | Box score |
| 01/30/21 | Buckhannon, WV | Alderson Broaddus 84, W.Va. Wesleyan 76 | Box score |
| 01/30/21 | Charleston, WV | Charleston 78, West Liberty 74 | Box score |
| 01/27/21 | West Liberty , WV | W.Va. State 100, West Liberty 96 | Box score |
| 01/27/21 | Charleston, WV | Charleston 98, Frostburg State 66 | Box score |
| 1/23/21 | Institute, WV | W.Va. State 92, Davis & Elkins 81 | Box score |
| 01/23/21 | Charleston, WV | Charleston 81, W.Va. Wesleyan 62 | Box score |
| 01/23/21 | Charlotte, NC | Frostburg State 71, Notre Dame 70 | Box score |
| 01/23/21 | Athens, WV | Alderson Broaddus 75, Concord 66 | Box score |
| 01/20/21 | Buckhannon, WV | W.Va. State 94, W.Va. Wesleyan 89 | Box score |
| 1/20/21 | Waco Center - | Glenville State 92, Wheeling 78 | Box score |
| 01/20/21 | Elkins, WV | Charleston 83, Davis & Elkins 74 | Box score |
| 01/20/21 | Athens, WV | Concord 91, West Liberty 83 | Box score |
| 1/20/21 | Rex Pyles Arena | Alderson Broaddus 90, Frostburg State 76 | Box score |
| 01/18/21 | South Euclid, OH | Notre Dame 75, Wheeling 69 | Box score |
| 01/16/21 | Buckhannon, WV | Glenville State 106, W.Va. Wesleyan 85 | Box score |
| 01/16/21 | Wheeling, WV | Fairmont State 95, Wheeling 60 | Box score |
| 01/16/21 | South Euclid, OH | Charleston 83, Notre Dame 60 | Box score |
| 01/16/21 | Elkins, WV | Davis & Elkins 67, Concord 56 | Box score |
| 1/16/21 | Rex Pyles Arena | W.Va. State 76, Alderson Broaddus 72 | Box score |
| 01/15/21 | West Liberty, W.Va. | West Liberty 134, Frostburg State 72 | Box score |
| 1/13/21 | Institute, WV | W.Va. State 93, Notre Dame 85 | Box score |
| 01/13/21 | Charleston, WV | Charleston 94, Alderson Broaddus 82 | Box score |
| 1/13/21 | Waco Center - | Glenville State 90, Davis & Elkins 85 | Box score |
| 01/13/21 | Fairmont, WV | West Liberty 96, Fairmont State 84 | Box score |
| 01/13/21 | Athens, WV | Concord 73, W.Va. Wesleyan 69 | Box score |
| 01/10/21 | Charlotte, NC | Frostburg State 81, W.Va. Wesleyan 77 | Box score |
| 1/10/21 | Rex Pyles Arena | West Liberty 123, Alderson Broaddus 73 | Box score |
| 1/10/21 | Waco Center - | Glenville State 72, Charleston 70 | Box score |
| 01/10/21 | Fairmont, WV | Fairmont State 87, Davis & Elkins 70 | Box score |
| 01/10/21 | Athens, WV | W.Va. State 89, Concord 74 | Box score |
| 01/07/21 | Buckhannon, WV | Fairmont State 110, W.Va. Wesleyan 85 | Box score |
| 01/07/21 | Wheeling, WV | Alderson Broaddus 85, Wheeling 79 | Box score |
| 1/7/21 | Institute, WV | Glenville State 117, W.Va. State 114 | Box score |
| 01/07/21 | West Liberty, W.Va. | West Liberty 98, Notre Dame 77 | Box score |
| 01/07/21 | Charleston, WV | Concord 64, Charleston 62 | Box score |
| 01/07/21 | Elkins, WV | Davis & Elkins 108, Frostburg State 100 | Box score |